Dr. Joshua Stern and the Cardiac Genetics Laboratory of Washington State University College of Veterinary Medicine are conducting a research study to identify the genetic mutation responsible for Subvalvular Aortic Stenosis (SAS) in Golden Retrievers. Advancements in technology have enabled us to become increasingly successful in identifying mutations responsible for breed specific heart disease and to develop DNA tests to help breeders reduce the incidence of disease.
This study requires DNA samples from 30 Golden Retrievers with a diagnosis of Subvalvular aortic stenosis (diagnosed by Doppler echocardiogram) and an additional 30 Goldens without Subvalvular aortic stenosis (as cleared by a cardiologist). Participants can be assured that their privacy will be protected and confidentiality maintained..
Your participation is greatly appreciated and questions are welcome!.
Please complete the form on page 2 and return along with the sample and required cardiologist report and pedigree to:
VCGL – WSU
Post Office Box 605
Pullman, WA 99163-0605
Sample collection
1. Please draw 2-3 ml of blood into an EDTA tube (lilac top). Most veterinary hospitals have these readily available, and many veterinarians are willing to waive their professional fee when obtaining samples for research purposes.
2. Please label tube well with dog’s call name and family last name.
3. Although this is not required for participation in the current study, ideally we would like to also bank DNA from Goldens affected with SAS in the CHIC DNA Repository for use in future research studies. If you are willing to do this, please download and complete both the Application form and the Health Survey from http://www.caninehealthinfo.org/dnabank.html and include both forms with sample. There is no fee for doing this.
The blood does not need to be mailed with ice packs or be shipped overnight. However, please try to send the sample within a few days by standard mail. Until the blood can be mailed, please keep it refrigerated (i.e., if the blood was drawn late Saturday and cannot be mailed until Monday, please refrigerate between Saturday and Monday).
Questions? Email: jsterndvm@gmail.com Phone: 614.390.1516
Right click on the link, and select ‘Save As’ to download the PDF document.
Golden Retriever Familial Subaortic Stenosis Study
Thank you very much for submitting a sample, we greatly appreciate it!